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An evaluation of electrocoagulation and thermal diffusion following radiofrequency microneedling using an in vivo porcine skin model
BACKGROUND: Few studies exist that examined the role of radiofrequency microneedling (RFMN) in skin electrocoagulation. This research utilized a porcine model to understand bipolar dermal delivery from an RFMN device. AIMS: The objective of this study was to elucidate and compare the dermal thermal...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048620/ https://www.ncbi.nlm.nih.gov/pubmed/32846042 http://dx.doi.org/10.1111/jocd.13690 |
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author | Wootten, Shaun Zawacki, Zosia E. Rheins, Lawrence Meschter, Carol Draelos, Zoe Diana |
author_facet | Wootten, Shaun Zawacki, Zosia E. Rheins, Lawrence Meschter, Carol Draelos, Zoe Diana |
author_sort | Wootten, Shaun |
collection | PubMed |
description | BACKGROUND: Few studies exist that examined the role of radiofrequency microneedling (RFMN) in skin electrocoagulation. This research utilized a porcine model to understand bipolar dermal delivery from an RFMN device. AIMS: The objective of this study was to elucidate and compare the dermal thermal effects of a RFMN device producing 1 and 2 MHz signal amplitudes, with respective voltage and current gradients, utilizing noninsulated and insulated needles by examining the histologic effects on porcine skin. METHODS: Two separate animal studies were conducted to evaluate the electrocoagulation and thermal diffusion effects using the RFMN device. The electrocoagulation effects were assessed histologically using hematoxylin and eosin (H&E) staining, and heating effects were assessed through thermal imaging. RESULTS: Histology results of the thermal injury induced by insulated needles demonstrated that 2 MHz resulted in a narrow and concentrated coagulation zone as compared to 1 MHz. Further, the 1 MHz insulated needle resulted in ovular shaped tissue coagulation as compared to 2 MHz tissue coagulation that was columnar. Finally, full thermal diffusion occurs seconds after the set RF conduction time. CONCLUSION: The findings showed that 1 MHz insulated needle produces larger coagulations with an increase in power level, the 1 MHz noninsulated array was comparable to the 2 MHz insulated array with similar histologic features, and heat dissipates seconds after the set conduction time. |
format | Online Article Text |
id | pubmed-8048620 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-80486202021-04-19 An evaluation of electrocoagulation and thermal diffusion following radiofrequency microneedling using an in vivo porcine skin model Wootten, Shaun Zawacki, Zosia E. Rheins, Lawrence Meschter, Carol Draelos, Zoe Diana J Cosmet Dermatol Chemical Peel BACKGROUND: Few studies exist that examined the role of radiofrequency microneedling (RFMN) in skin electrocoagulation. This research utilized a porcine model to understand bipolar dermal delivery from an RFMN device. AIMS: The objective of this study was to elucidate and compare the dermal thermal effects of a RFMN device producing 1 and 2 MHz signal amplitudes, with respective voltage and current gradients, utilizing noninsulated and insulated needles by examining the histologic effects on porcine skin. METHODS: Two separate animal studies were conducted to evaluate the electrocoagulation and thermal diffusion effects using the RFMN device. The electrocoagulation effects were assessed histologically using hematoxylin and eosin (H&E) staining, and heating effects were assessed through thermal imaging. RESULTS: Histology results of the thermal injury induced by insulated needles demonstrated that 2 MHz resulted in a narrow and concentrated coagulation zone as compared to 1 MHz. Further, the 1 MHz insulated needle resulted in ovular shaped tissue coagulation as compared to 2 MHz tissue coagulation that was columnar. Finally, full thermal diffusion occurs seconds after the set RF conduction time. CONCLUSION: The findings showed that 1 MHz insulated needle produces larger coagulations with an increase in power level, the 1 MHz noninsulated array was comparable to the 2 MHz insulated array with similar histologic features, and heat dissipates seconds after the set conduction time. John Wiley and Sons Inc. 2020-09-07 2021-04 /pmc/articles/PMC8048620/ /pubmed/32846042 http://dx.doi.org/10.1111/jocd.13690 Text en © 2020 Aesthetics Biomedical, Inc. Journal of Cosmetic Dermatology published by Wiley Periodicals LLC https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Chemical Peel Wootten, Shaun Zawacki, Zosia E. Rheins, Lawrence Meschter, Carol Draelos, Zoe Diana An evaluation of electrocoagulation and thermal diffusion following radiofrequency microneedling using an in vivo porcine skin model |
title | An evaluation of electrocoagulation and thermal diffusion following radiofrequency microneedling using an in vivo porcine skin model |
title_full | An evaluation of electrocoagulation and thermal diffusion following radiofrequency microneedling using an in vivo porcine skin model |
title_fullStr | An evaluation of electrocoagulation and thermal diffusion following radiofrequency microneedling using an in vivo porcine skin model |
title_full_unstemmed | An evaluation of electrocoagulation and thermal diffusion following radiofrequency microneedling using an in vivo porcine skin model |
title_short | An evaluation of electrocoagulation and thermal diffusion following radiofrequency microneedling using an in vivo porcine skin model |
title_sort | evaluation of electrocoagulation and thermal diffusion following radiofrequency microneedling using an in vivo porcine skin model |
topic | Chemical Peel |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048620/ https://www.ncbi.nlm.nih.gov/pubmed/32846042 http://dx.doi.org/10.1111/jocd.13690 |
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