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Anti‐β2‐glycoprotein I and anti‐prothrombin antibodies cause lupus anticoagulant through different mechanisms of action
BACKGROUND: The presence of lupus anticoagulant (LA) is an independent risk factor for thrombosis. This laboratory phenomenon is detected as a phospholipid‐dependent prolongation of the clotting time and is caused by autoantibodies against beta2‐glycoprotein I (β2GPI) or prothrombin. How these autoa...
Autores principales: | Noordermeer, Tessa, Molhoek, Jessica E., Schutgens, Roger E. G., Sebastian, Silvie A. E., Drost‐Verhoef, Sandra, van Wesel, Annet C. W., de Groot, Philip G., Meijers, Joost C. M., Urbanus, Rolf T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048633/ https://www.ncbi.nlm.nih.gov/pubmed/33421291 http://dx.doi.org/10.1111/jth.15241 |
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