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Synthesis of [4S‐(2)H]NADH, [4R‐(2)H]NADH, [4‐(2)H(2)]NADH and [4‐(2)H]NAD(+) cofactors through heterogeneous biocatalysis in heavy water
This practitioner protocol describes the synthesis of a family of deuterated nicotinamide cofactors: [4S‐(2)H]NADH, [4R‐(2)H]NADH, [4‐(2)H(2)]NADH and [4‐(2)H]NAD(+). The application of a recently developed H(2)‐driven heterogeneous biocatalyst enables the cofactors to be prepared with high (>90%...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048645/ https://www.ncbi.nlm.nih.gov/pubmed/33497029 http://dx.doi.org/10.1002/jlcr.3899 |