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HIV-1(LAI) Nef blocks the development of hematopoietic stem/progenitor cells into T lymphoid cells

OBJECTIVE: Despite successful antiviral therapy, the recovery of CD4(+) T cells may not be complete in certain HIV-1-infected individuals. In our previous work with humanized mice infected with CXCR4-tropic HIV-1(LAI) (LAI), viral protein Nef was found the major factor determining rapid loss of both...

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Detalles Bibliográficos
Autores principales:	Zou, Wei, Xing, Juanjuan, Wang, Fen, Chen, Xinping, Liu, Qian, Wang, Jinyong, Zou, Shijie, Chen, Limin, Fu, Xin, Zhou, Zhengping, Wan, Zhikai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2021
Materias:	Basic Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048728/ https://www.ncbi.nlm.nih.gov/pubmed/33587447 http://dx.doi.org/10.1097/QAD.0000000000002837

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