Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy

Degeneration of the cartilage endplate (CEP) induces intervertebral disc degeneration (IVDD). Nucleus pulposus cell (NPC) apoptosis is also an important exacerbating factor in IVDD, but the cascade mechanism in IVDD is not clear. We investigated the apoptosis of NPCs and IVDD when stimulated by norm...

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Detalles Bibliográficos
Autores principales: Luo, Liwen, Jian, Xiuying, Sun, Hui, Qin, Jinghao, Wang, Yanqiu, Zhang, Ji, Shen, Zigang, Yang, Di, Li, Changqing, Zhao, Ping, Liu, MingHan, Tian, Zhiqiang, Zhou, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Tissue‐specific Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048856/
https://www.ncbi.nlm.nih.gov/pubmed/33459443
http://dx.doi.org/10.1002/stem.3322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048856/
https://www.ncbi.nlm.nih.gov/pubmed/33459443
http://dx.doi.org/10.1002/stem.3322

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