Physiologically‐Based Pharmacokinetic Modeling Combined with Swiss HIV Cohort Study Data Supports No Dose Adjustment of Bictegravir in Elderly Individuals Living With HIV

Clinical studies in aging people living with HIV (PLWH) are sparse for the novel integrase inhibitor bictegravir, leading to some uncertainty about dosing recommendations for elderly PLWH. The objective of this study was to investigate the continuous impact of aging on bictegravir pharmacokinetics b...

Descripción completa

Detalles Bibliográficos
Autores principales: Stader, Felix, Courlet, Perrine, Decosterd, Laurent A., Battegay, Manuel, Marzolini, Catia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048864/
https://www.ncbi.nlm.nih.gov/pubmed/33521960
http://dx.doi.org/10.1002/cpt.2178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048864/
https://www.ncbi.nlm.nih.gov/pubmed/33521960
http://dx.doi.org/10.1002/cpt.2178

Ejemplares similares