The impact of a 1‐hour time interval between pazopanib and subsequent intake of gastric acid suppressants on pazopanib exposure

Co‐treatment with gastric acid suppressants (GAS) in patients taking anticancer drugs that exhibit pH‐dependant absorption may lead to decreased drug exposure and may hamper drug efficacy. In our study, we investigated whether a 1‐hour time interval between subsequent intake of pazopanib and GAS cou...

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Detalles Bibliográficos
Autores principales: Krens, Stefanie D., Lubberman, Floor J. E., van Egmond, Marthe, Jansman, Frank G. A., Burger, David M., Hamberg, Paul, Vervenne, Walter L., Gelderblom, Hans, van der Graaf, Winette T. A., Desar, Ingrid M. E., van Herpen, Carla M. L., van Erp, Nielka P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Cancer Therapy and Prevention
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048885/
https://www.ncbi.nlm.nih.gov/pubmed/33428771
http://dx.doi.org/10.1002/ijc.33469

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