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Neurocognitive functioning in patients with conversion disorder/functional neurological disorder

Neurocognitive symptoms are common in individuals with somatic symptom and related disorders (SSRD), but little is known about the specific impairments in neurocognitive domains in patients with conversion disorder (CD)/functional neurological disorder (FND). This study examines neurocognitive funct...

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Autores principales: de Vroege, Lars, Koppenol, Iris, Kop, Willem Johan, Riem, Madelon M.E., van der Feltz‐Cornelis, Christina Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048909/
https://www.ncbi.nlm.nih.gov/pubmed/32223071
http://dx.doi.org/10.1111/jnp.12206
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author de Vroege, Lars
Koppenol, Iris
Kop, Willem Johan
Riem, Madelon M.E.
van der Feltz‐Cornelis, Christina Maria
author_facet de Vroege, Lars
Koppenol, Iris
Kop, Willem Johan
Riem, Madelon M.E.
van der Feltz‐Cornelis, Christina Maria
author_sort de Vroege, Lars
collection PubMed
description Neurocognitive symptoms are common in individuals with somatic symptom and related disorders (SSRD), but little is known about the specific impairments in neurocognitive domains in patients with conversion disorder (CD)/functional neurological disorder (FND). This study examines neurocognitive functioning in patients with CD/FND compared to patients with other SSRD. The sample consisted of 318 patients. Twenty‐nine patients were diagnosed with CD/FND, mean age 42.4, standard deviation (SD) = 13.8 years, 79.3% women, and 289 patients had other SSRD (mean age 42.1, SD = 13.3, 60.2% women). Patients completed a neuropsychological test battery that addressed a broad range of neurocognitive domains, including information processing speed, attention and executive functioning. Patients with CD/FND had clinically significant neurocognitive deficits in all neurocognitive domains based on normative data comparison. Patients with CD/FND also performed significantly worse than patients with other SSRD on information processing speed (Digit Symbol Substitution Test (V = .115, p = .035), Stroop Color–Word Test (SCWT) card 1 (V = .190, p = .006), and SCWT card 2 (V = .244, p < .001). No CD/FND vs. other SSRD differences were observed in other neurocognitive domains. These findings indicate the patients with CD/FND perform worse on information processing speed tests compared to patients with other SSRD.
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spelling pubmed-80489092021-04-20 Neurocognitive functioning in patients with conversion disorder/functional neurological disorder de Vroege, Lars Koppenol, Iris Kop, Willem Johan Riem, Madelon M.E. van der Feltz‐Cornelis, Christina Maria J Neuropsychol Original Articles Neurocognitive symptoms are common in individuals with somatic symptom and related disorders (SSRD), but little is known about the specific impairments in neurocognitive domains in patients with conversion disorder (CD)/functional neurological disorder (FND). This study examines neurocognitive functioning in patients with CD/FND compared to patients with other SSRD. The sample consisted of 318 patients. Twenty‐nine patients were diagnosed with CD/FND, mean age 42.4, standard deviation (SD) = 13.8 years, 79.3% women, and 289 patients had other SSRD (mean age 42.1, SD = 13.3, 60.2% women). Patients completed a neuropsychological test battery that addressed a broad range of neurocognitive domains, including information processing speed, attention and executive functioning. Patients with CD/FND had clinically significant neurocognitive deficits in all neurocognitive domains based on normative data comparison. Patients with CD/FND also performed significantly worse than patients with other SSRD on information processing speed (Digit Symbol Substitution Test (V = .115, p = .035), Stroop Color–Word Test (SCWT) card 1 (V = .190, p = .006), and SCWT card 2 (V = .244, p < .001). No CD/FND vs. other SSRD differences were observed in other neurocognitive domains. These findings indicate the patients with CD/FND perform worse on information processing speed tests compared to patients with other SSRD. John Wiley and Sons Inc. 2020-03-29 2021-03 /pmc/articles/PMC8048909/ /pubmed/32223071 http://dx.doi.org/10.1111/jnp.12206 Text en © 2020 The Authors. Journal of Neuropsychology published by John Wiley & Sons Ltd on behalf of British Psychological Society https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
de Vroege, Lars
Koppenol, Iris
Kop, Willem Johan
Riem, Madelon M.E.
van der Feltz‐Cornelis, Christina Maria
Neurocognitive functioning in patients with conversion disorder/functional neurological disorder
title Neurocognitive functioning in patients with conversion disorder/functional neurological disorder
title_full Neurocognitive functioning in patients with conversion disorder/functional neurological disorder
title_fullStr Neurocognitive functioning in patients with conversion disorder/functional neurological disorder
title_full_unstemmed Neurocognitive functioning in patients with conversion disorder/functional neurological disorder
title_short Neurocognitive functioning in patients with conversion disorder/functional neurological disorder
title_sort neurocognitive functioning in patients with conversion disorder/functional neurological disorder
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048909/
https://www.ncbi.nlm.nih.gov/pubmed/32223071
http://dx.doi.org/10.1111/jnp.12206
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