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Platelet Glycoprotein Ib α‐Chain as a Putative Therapeutic Target for Juvenile Idiopathic Arthritis: A Mendelian Randomization Study

OBJECTIVE: To ascertain the role of platelet glycoprotein Ib α‐chain (GPIbα) plasma protein levels in cardiovascular, autoimmune, and autoinflammatory diseases and whether its effects are mediated by platelet count. METHODS: We performed a two‐sample Mendelian randomization (MR) study, using both a...

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Detalles Bibliográficos
Autores principales: Luo, Shan, Clarke, Sarah L. N., Ramanan, Athimalaipet V., Thompson, Susan D., Langefeld, Carl D., Marion, Miranda C., Grom, Alexei A., Schooling, C. Mary, Gaunt, Tom R., Yeung, Shiu Lun Au, Zheng, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048917/
https://www.ncbi.nlm.nih.gov/pubmed/33079445
http://dx.doi.org/10.1002/art.41561