Cargando…

Enantioselective Nickel‐Catalyzed anti‐Arylmetallative Cyclizations onto Acyclic Ketones

Domino reactions involving nickel‐catalyzed additions of (hetero)arylboronic acids to alkynes, followed by cyclization of the alkenylnickel intermediates onto tethered acyclic ketones to give chiral tertiary‐alcohol‐containing products in high enantioselectivities, are described. The reversible E/Z...

Descripción completa

Detalles Bibliográficos
Autores principales:	Green, Harley, Argent, Stephen P., Lam, Hon Wai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048927/ https://www.ncbi.nlm.nih.gov/pubmed/33533065 http://dx.doi.org/10.1002/chem.202100143

Ejemplares similares

Enantioselective nickel-catalyzed arylative and alkenylative intramolecular 1,2-allylations of tethered allene–ketones
por: Di Sanza, Riccardo, et al.
Publicado: (2020)

Enantioselective Nickel-Catalyzed anti-Carbometallative Cyclizations of Alkynyl Electrophiles Enabled by Reversible Alkenylnickel E/Z Isomerization
por: Clarke, Christopher, et al.
Publicado: (2016)

Nickel‐Catalyzed Arylative Cyclizations of Alkyne‐ and Allene‐Tethered Electrophiles using Arylboron Reagents
por: Gillbard, Simone M., et al.
Publicado: (2022)

Enantioselective Synthesis of Chiral Cyclopent‐2‐enones by Nickel‐Catalyzed Desymmetrization of Malonate Esters
por: Karad, Somnath Narayan, et al.
Publicado: (2018)

Enantioselective synthesis of bicyclo[3.n.1]alkanes by chiral phosphoric acid-catalyzed desymmetrizing Michael cyclizations
por: Burns, Alan R., et al.
Publicado: (2015)

Understanding the unique reactivity patterns of nickel/JoSPOphos manifold in the nickel-catalyzed enantioselective C–H cyclization of imidazoles
por: Liu, Jian-Biao, et al.
Publicado: (2020)

Catalytic enantioselective arylative cyclizations of alkynyl 1,3-diketones by 1,4-rhodium(i) migration
por: Groves, Alistair, et al.
Publicado: (2020)

Nickel-catalyzed enantioselective arylation of pyridine
por: Lutz, J. Patrick, et al.
Publicado: (2016)

Chromium(II)-catalyzed enantioselective arylation of ketones
por: Wang, Gang, et al.
Publicado: (2016)

Enantioselective Copper‐Catalyzed Borylative Cyclization for the Synthesis of Quinazolinones
por: Dherbassy, Quentin, et al.
Publicado: (2021)

Boron-Catalyzed, Diastereo- and Enantioselective Allylation of Ketones with Allenes
por: Nicholson, Kieran, et al.
Publicado: (2022)

Enantioselective Nickel‐Catalyzed Intramolecular Allylic Alkenylations Enabled by Reversible Alkenylnickel E/Z Isomerization
por: Yap, Connor, et al.
Publicado: (2017)

Cobalt-catalyzed enantioselective desymmetrizing reductive cyclization of alkynyl cyclodiketones
por: Liang, Ren-Xiao, et al.
Publicado: (2023)

Cobalt-catalyzed enantioselective intramolecular reductive cyclization via electrochemistry
por: Gao, Shiquan, et al.
Publicado: (2023)

Asymmetric construction of acyclic quaternary stereocenters via direct enantioselective additions of α-alkynyl ketones to allenamides
por: Wang, Jiawen, et al.
Publicado: (2021)

Iridium-Catalyzed Arylative Cyclization of Alkynones by 1,4-Iridium Migration**
por: Partridge, Benjamin M, et al.
Publicado: (2014)

Computational Analysis of Enantioselective Pd-Catalyzed α-Arylation of Ketones
por: Orlandi, Manuel, et al.
Publicado: (2020)

Nickel-catalyzed cyclization of alkyne-nitriles with organoboronic acids involving anti-carbometalation of alkynes
por: Zhang, Xingjie, et al.
Publicado: (2016)

Nickel-catalyzed enantioselective α-heteroarylation of ketones via C–F bond activation to construct all-carbon quaternary stereocenters
por: Gu, Xiaodong, et al.
Publicado: (2022)

Nickel-Catalyzed Stereoselective Alkenylation of Ketones Mediated by Hydrazine
por: Xia, Shumei, et al.
Publicado: (2022)

Nickel-catalyzed enantioselective 1,2-vinylboration of styrenes
por: Ye, Yang, et al.
Publicado: (2021)

Nickel-catalyzed enantioselective reductive carbo-acylation of alkenes
por: Lan, Yun, et al.
Publicado: (2020)

Gold and BINOL-Phosphoric Acid Catalyzed Enantioselective Hydroamination/N-Sulfonyliminium Cyclization Cascade
por: Gregory, Alex W., et al.
Publicado: (2013)

Enantioselective Cu(I)-catalyzed borylative cyclization of enone-tethered cyclohexadienones and mechanistic insights
por: Jadhav, Sandip B., et al.
Publicado: (2022)

Asymmetric Gold(I)‐Catalyzed Tandem Hydroarylation–Nazarov Cyclization: Enantioselective Access to Cyclopentenones
por: Solas, Marta, et al.
Publicado: (2022)

Enantioselective Synthesis of Spirooxindole Enols: Regioselective and Asymmetric [3+2] Cyclization of 3‐Isothiocyanato Oxindoles with Dibenzylidene Ketones
por: Du, Dan, et al.
Publicado: (2016)

Nickel-catalyzed enantioselective vinylation of aryl 2-azaallyl anions
por: Duan, Shengzu, et al.
Publicado: (2021)

Enantioselective nickel-catalyzed dicarbofunctionalization of 3,3,3-trifluoropropene
por: Li, Yun-Ze, et al.
Publicado: (2022)

Synthesis of Polycyclic Ring Systems Using Transition Metal Catalyzed Cyclizations of Diazo Alkynyl Ketones ‡
por: Padwa, Albert
Publicado: (2000)

Enantioselective Total Synthesis of (−)-Nardoaristolone B via a Gold(I)-Catalyzed Oxidative Cyclization
por: Homs, Anna, et al.
Publicado: (2015)

Enantioselective Nazarov cyclization of indole enones cooperatively catalyzed by Lewis acids and chiral Brønsted acids
por: Wang, Guo-Peng, et al.
Publicado: (2017)

Copper-catalyzed enantioselective diyne cyclization via C(sp(2))–O bond cleavage
por: Zhou, Ji-Jia, et al.
Publicado: (2023)

Cyano-borrowing reaction: nickel-catalyzed direct conversion of cyanohydrins and aldehydes/ketones to β-cyano ketone
por: Li, Zhao-Feng, et al.
Publicado: (2019)

Direct and Enantioselective Aldol Reactions Catalyzed by Chiral Nickel(II) Complexes
por: Kennington, Stuart C. D., et al.
Publicado: (2021)

Enantioselective Synthesis of Spiroindenes by Enol-Directed Rhodium(III)-Catalyzed C–H Functionalization and Spiroannulation
por: Reddy Chidipudi, Suresh, et al.
Publicado: (2015)

Traceless Rhodium‐Catalyzed Hydroacylation Using Alkyl Aldehydes: The Enantioselective Synthesis of β‐Aryl Ketones
por: Bouisseau, Anaïs, et al.
Publicado: (2016)

Synthesis of 1,2-Aminoalcohols through Enantioselective Aminoallylation of Ketones by Cu-Catalyzed Reductive Coupling
por: Klake, Raphael K., et al.
Publicado: (2021)

Enantioselective Michael addition of malonates to α,β-unsaturated ketones catalyzed by 1,2-diphenylethanediamine
por: Wang, Wei, et al.
Publicado: (2018)

Nickel(II)-catalyzed asymmetric photoenolization/Mannich reaction of (2-alkylphenyl) ketones
por: Yang, Liangkun, et al.
Publicado: (2022)

Nickel-catalyzed direct stereoselective α-allylation of ketones with non-conjugated dienes
por: Cao, Yi-Xuan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_88ct4apn7k52nhqns18dea8lhg