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PLD1 and PLD2 differentially regulate the balance of macrophage polarization in inflammation and tissue injury

Phospholipase D (PLD) isoforms PLD1 and PLD2 serve as the primary nodes where diverse signaling pathways converge. However, their isoform‐specific functions remain unclear. We showed that PLD1 and PLD2 selectively couple to toll‐like receptor 4 (TLR4) and interleukin 4 receptor (IL‐4R) and different...

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Detalles Bibliográficos
Autores principales:	Hwang, Won Chan, Seo, Seol Hwa, Kang, Minju, Kang, Rae Hee, Di Paolo, Gilbert, Choi, Kang‐Yell, Min, Do Sik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048932/ https://www.ncbi.nlm.nih.gov/pubmed/33368247 http://dx.doi.org/10.1002/jcp.30224

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