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Large‐Peptide Permeation Through a Membrane Channel: Understanding Protamine Translocation Through CymA from Klebsiella Oxytoca
Quantifying the passage of the large peptide protamine (Ptm) across CymA, a passive channel for cyclodextrin uptake, is in the focus of this study. Using a reporter‐pair‐based fluorescence membrane assay we detected the entry of Ptm into liposomes containing CymA. The kinetics of the Ptm entry was i...
Autores principales: | Pangeni, Sushil, Prajapati, Jigneshkumar Dahyabhai, Bafna, Jayesh, Nilam, Mohamed, Nau, Werner M., Kleinekathöfer, Ulrich, Winterhalter, Mathias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049027/ https://www.ncbi.nlm.nih.gov/pubmed/33580541 http://dx.doi.org/10.1002/anie.202016943 |
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