Simplified Monopalmitoyl Toll‐like Receptor 2 Ligand Mini‐UPam for Self‐Adjuvanting Neoantigen‐Based Synthetic Cancer Vaccines

Synthetic vaccines, based on antigenic peptides that comprise MHC−I and MHC‐II T‐cell epitopes expressed by tumors, show great promise for the immunotherapy of cancer. For optimal immunogenicity, the synthetic peptides (SPs) should be adjuvanted with suitable immunostimulatory additives. Previously,...

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Detalles Bibliográficos
Autores principales: van den Ende, Thomas C., Heuts, Jeroen M. M., Gential, Geoffroy P. P., Visser, Marten, van de Graaff, Michel J., Ho, Nataschja I., Jiskoot, Wim, Valentijn, A. Rob P. M., Meeuwenoord, Nico J., Overkleeft, Herman S., Codée, Jeroen D. C., van der Burg, Sjoerd H., Verdegaal, Els M. E., van der Marel, Gijsbert A., Ossendorp, Ferry, Filippov, Dmitri V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049070/
https://www.ncbi.nlm.nih.gov/pubmed/33180981
http://dx.doi.org/10.1002/cbic.202000687

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