Breast Tumors Maintain a Reservoir of Subclonal Diversity During Expansion

Our knowledge of copy number evolution during the expansion of primary breast tumors is limited(1,2). To investigate this process, we developed a single cell, single-molecule DNA sequencing method and performed copy number analysis of 16,178 single cells from 8 triple-negative breast cancers (TNBCs)...

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Detalles Bibliográficos
Autores principales: Minussi, Darlan Conterno, Nicholson, Michael D., Ye, Hanghui, Davis, Alexander, Wang, Kaile, Baker, Toby, Tarabichi, Maxime, Sei, Emi, Du, Haowei, Rabbani, Mashiat, Peng, Cheng, Hu, Min, Bai, Shanshan, Lin, Yu-wei, Schalck, Aislyn, Multani, Asha, Ma, Jin, McDonald, Thomas O., Casasent, Anna, Barrera, Angelica, Chen, Hui, Lim, Bora, Arun, Banu, Meric-Bernstam, Funda, Van Loo, Peter, Michor, Franziska, Navin, Nicholas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049101/
https://www.ncbi.nlm.nih.gov/pubmed/33762732
http://dx.doi.org/10.1038/s41586-021-03357-x

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