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Immuno-PET Detects Changes in Multi-RTK Tumor Cell Expression Levels in Response to Targeted Kinase Inhibition

Receptor tyrosine kinase (RTK) coexpression facilitates tumor resistance due to redundancies in the phosphatidylinositol-3′-kinase/protein kinase B and KRAS/extracellular-signal–regulated kinase signaling pathways, among others. Crosstalk between the oncogenic RTK hepatocyte growth factor receptor (...

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Detalles Bibliográficos
Autores principales: Pereira, Patricia M.R., Norfleet, Jalen, Lewis, Jason S., Escorcia, Freddy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Nuclear Medicine 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049345/
https://www.ncbi.nlm.nih.gov/pubmed/32646879
http://dx.doi.org/10.2967/jnumed.120.244897