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The role of nanotechnology in current COVID-19 outbreak

COVID-19 has recently become one of the most challenging pandemics of the last century with deadly outcomes and a high rate of reproduction number. It emphasizes the critical need for the designing of efficient vaccines to prevent virus infection, early and fast diagnosis by the high sensitivity and...

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Autores principales: Tavakol, Shima, Zahmatkeshan, Masoumeh, Mohammadinejad, Reza, Mehrzadi, Saeed, Joghataei, Mohammad T., Alavijeh, Mo S., Seifalian, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049405/
https://www.ncbi.nlm.nih.gov/pubmed/33880422
http://dx.doi.org/10.1016/j.heliyon.2021.e06841
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author Tavakol, Shima
Zahmatkeshan, Masoumeh
Mohammadinejad, Reza
Mehrzadi, Saeed
Joghataei, Mohammad T.
Alavijeh, Mo S.
Seifalian, Alexander
author_facet Tavakol, Shima
Zahmatkeshan, Masoumeh
Mohammadinejad, Reza
Mehrzadi, Saeed
Joghataei, Mohammad T.
Alavijeh, Mo S.
Seifalian, Alexander
author_sort Tavakol, Shima
collection PubMed
description COVID-19 has recently become one of the most challenging pandemics of the last century with deadly outcomes and a high rate of reproduction number. It emphasizes the critical need for the designing of efficient vaccines to prevent virus infection, early and fast diagnosis by the high sensitivity and selectivity diagnostic kits, and effective antiviral and protective therapeutics to decline and eliminate the viral load and side effects derived from tissue damages. Therefore, non-toxic antiviral nanoparticles (NPs) have been under development for clinical application to prevent and treat COVID-19. NPs showed great promise to provide nano vaccines against viral infections. Here, we discuss the potentials of NPs that may be applied as a drug itself or as a platform for the aim of drug and vaccine repurposing and development. Meanwhile, the advanced strategies based on NPs to detect viruses will be described with the goal of encouraging scientists to design effective and cost-benefit nanoplatforms for prevention, diagnosis, and treatment.
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spelling pubmed-80494052021-04-16 The role of nanotechnology in current COVID-19 outbreak Tavakol, Shima Zahmatkeshan, Masoumeh Mohammadinejad, Reza Mehrzadi, Saeed Joghataei, Mohammad T. Alavijeh, Mo S. Seifalian, Alexander Heliyon Review Article COVID-19 has recently become one of the most challenging pandemics of the last century with deadly outcomes and a high rate of reproduction number. It emphasizes the critical need for the designing of efficient vaccines to prevent virus infection, early and fast diagnosis by the high sensitivity and selectivity diagnostic kits, and effective antiviral and protective therapeutics to decline and eliminate the viral load and side effects derived from tissue damages. Therefore, non-toxic antiviral nanoparticles (NPs) have been under development for clinical application to prevent and treat COVID-19. NPs showed great promise to provide nano vaccines against viral infections. Here, we discuss the potentials of NPs that may be applied as a drug itself or as a platform for the aim of drug and vaccine repurposing and development. Meanwhile, the advanced strategies based on NPs to detect viruses will be described with the goal of encouraging scientists to design effective and cost-benefit nanoplatforms for prevention, diagnosis, and treatment. Elsevier 2021-04-15 /pmc/articles/PMC8049405/ /pubmed/33880422 http://dx.doi.org/10.1016/j.heliyon.2021.e06841 Text en © 2021 Published by Elsevier Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Tavakol, Shima
Zahmatkeshan, Masoumeh
Mohammadinejad, Reza
Mehrzadi, Saeed
Joghataei, Mohammad T.
Alavijeh, Mo S.
Seifalian, Alexander
The role of nanotechnology in current COVID-19 outbreak
title The role of nanotechnology in current COVID-19 outbreak
title_full The role of nanotechnology in current COVID-19 outbreak
title_fullStr The role of nanotechnology in current COVID-19 outbreak
title_full_unstemmed The role of nanotechnology in current COVID-19 outbreak
title_short The role of nanotechnology in current COVID-19 outbreak
title_sort role of nanotechnology in current covid-19 outbreak
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049405/
https://www.ncbi.nlm.nih.gov/pubmed/33880422
http://dx.doi.org/10.1016/j.heliyon.2021.e06841
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