A C. elegans genome-wide RNAi screen for altered levamisole sensitivity identifies genes required for muscle function

At the neuromuscular junction (NMJ), postsynaptic ionotropic acetylcholine receptors (AChRs) transduce a chemical signal released from a cholinergic motor neuron into an electrical signal to induce muscle contraction. To identify regulators of postsynaptic function, we conducted a genome-wide RNAi s...

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Detalles Bibliográficos
Autores principales: Chaya, Timothy, Patel, Shrey, Smith, Erin M, Lam, Andy, Miller, Elaine N, Clupper, Michael, Kervin, Kirsten, Tanis, Jessica E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Mutant Screen Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049432/
https://www.ncbi.nlm.nih.gov/pubmed/33713125
http://dx.doi.org/10.1093/g3journal/jkab047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049432/
https://www.ncbi.nlm.nih.gov/pubmed/33713125
http://dx.doi.org/10.1093/g3journal/jkab047

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