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Interpretable Feature Generation in ECG Using a Variational Autoencoder

We propose a method for generating an electrocardiogram (ECG) signal for one cardiac cycle using a variational autoencoder. Our goal was to encode the original ECG signal using as few features as possible. Using this method we extracted a vector of new 25 features, which in many cases can be interpr...

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Detalles Bibliográficos
Autores principales: Kuznetsov, V. V., Moskalenko, V. A., Gribanov, D. V., Zolotykh, Nikolai Yu.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049433/
https://www.ncbi.nlm.nih.gov/pubmed/33868375
http://dx.doi.org/10.3389/fgene.2021.638191
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author Kuznetsov, V. V.
Moskalenko, V. A.
Gribanov, D. V.
Zolotykh, Nikolai Yu.
author_facet Kuznetsov, V. V.
Moskalenko, V. A.
Gribanov, D. V.
Zolotykh, Nikolai Yu.
author_sort Kuznetsov, V. V.
collection PubMed
description We propose a method for generating an electrocardiogram (ECG) signal for one cardiac cycle using a variational autoencoder. Our goal was to encode the original ECG signal using as few features as possible. Using this method we extracted a vector of new 25 features, which in many cases can be interpreted. The generated ECG has quite natural appearance. The low value of the Maximum Mean Discrepancy metric, 3.83 × 10(−3), indicates good quality of ECG generation too. The extracted new features will help to improve the quality of automatic diagnostics of cardiovascular diseases. Generating new synthetic ECGs will allow us to solve the issue of the lack of labeled ECG for using them in supervised learning.
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spelling pubmed-80494332021-04-16 Interpretable Feature Generation in ECG Using a Variational Autoencoder Kuznetsov, V. V. Moskalenko, V. A. Gribanov, D. V. Zolotykh, Nikolai Yu. Front Genet Genetics We propose a method for generating an electrocardiogram (ECG) signal for one cardiac cycle using a variational autoencoder. Our goal was to encode the original ECG signal using as few features as possible. Using this method we extracted a vector of new 25 features, which in many cases can be interpreted. The generated ECG has quite natural appearance. The low value of the Maximum Mean Discrepancy metric, 3.83 × 10(−3), indicates good quality of ECG generation too. The extracted new features will help to improve the quality of automatic diagnostics of cardiovascular diseases. Generating new synthetic ECGs will allow us to solve the issue of the lack of labeled ECG for using them in supervised learning. Frontiers Media S.A. 2021-04-01 /pmc/articles/PMC8049433/ /pubmed/33868375 http://dx.doi.org/10.3389/fgene.2021.638191 Text en Copyright © 2021 Kuznetsov, Moskalenko, Gribanov and Zolotykh. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Genetics
Kuznetsov, V. V.
Moskalenko, V. A.
Gribanov, D. V.
Zolotykh, Nikolai Yu.
Interpretable Feature Generation in ECG Using a Variational Autoencoder
title Interpretable Feature Generation in ECG Using a Variational Autoencoder
title_full Interpretable Feature Generation in ECG Using a Variational Autoencoder
title_fullStr Interpretable Feature Generation in ECG Using a Variational Autoencoder
title_full_unstemmed Interpretable Feature Generation in ECG Using a Variational Autoencoder
title_short Interpretable Feature Generation in ECG Using a Variational Autoencoder
title_sort interpretable feature generation in ecg using a variational autoencoder
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049433/
https://www.ncbi.nlm.nih.gov/pubmed/33868375
http://dx.doi.org/10.3389/fgene.2021.638191
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