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Tau post-translational modifications in wildtype and human amyloid precursor protein transgenic mice

The microtubule-associated protein tau has been implicated in the pathogenesis of Alzheimer's disease (AD) and other neurodegenerative disorders. Reducing tau levels ameliorates AD-related synaptic, network, and behavioral abnormalities in human amyloid precursor protein (hAPP) transgenic mice....

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Detalles Bibliográficos
Autores principales:	Morris, Meaghan, Knudsen, Giselle M., Maeda, Sumihiro, Trinidad, Jonathan C., Ioanoviciu, Alexandra, Burlingame, Alma L., Mucke, Lennart
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049446/ https://www.ncbi.nlm.nih.gov/pubmed/26192747 http://dx.doi.org/10.1038/nn.4067

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