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Neuraminidase B controls neuraminidase A-dependent mucus production and evasion

Binding of Streptococcus pneumoniae (Spn) to nasal mucus leads to entrapment and clearance via mucociliary activity during colonization. To identify Spn factors allowing for evasion of mucus binding, we used a solid-phase adherence assay with immobilized mucus of human and murine origin. Spn bound l...

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Detalles Bibliográficos
Autores principales: Hammond, Alexandria J., Binsker, Ulrike, Aggarwal, Surya D., Ortigoza, Mila Brum, Loomis, Cynthia, Weiser, Jeffrey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049478/
https://www.ncbi.nlm.nih.gov/pubmed/33819312
http://dx.doi.org/10.1371/journal.ppat.1009158