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Neuraminidase B controls neuraminidase A-dependent mucus production and evasion
Binding of Streptococcus pneumoniae (Spn) to nasal mucus leads to entrapment and clearance via mucociliary activity during colonization. To identify Spn factors allowing for evasion of mucus binding, we used a solid-phase adherence assay with immobilized mucus of human and murine origin. Spn bound l...
Autores principales: | Hammond, Alexandria J., Binsker, Ulrike, Aggarwal, Surya D., Ortigoza, Mila Brum, Loomis, Cynthia, Weiser, Jeffrey N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049478/ https://www.ncbi.nlm.nih.gov/pubmed/33819312 http://dx.doi.org/10.1371/journal.ppat.1009158 |
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