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Impact of cognitive intervention on cognitive symptoms and quality of life in idiopathic Parkinson’s disease: a randomized and controlled study

Pharmacological treatments for mild cognitive impairment (MCI), are lacking, and alternative approaches have been implemented, including cognitive training (CT). OBJECTIVE: To determine the impact of CT on cognitive and quality of life measures in patients with Parkinson’s disease (PD) who were seen...

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Autores principales: Sousa, Nariana Mattos Figueiredo, Neri, Ana Cristina da Mata, Brandi, Ivar Viana, Brucki, Sonia Maria Dozzi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação de Neurologia Cognitiva e do Comportamento 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049575/
https://www.ncbi.nlm.nih.gov/pubmed/33907597
http://dx.doi.org/10.1590/1980-57642021dn15-010005
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author Sousa, Nariana Mattos Figueiredo
Neri, Ana Cristina da Mata
Brandi, Ivar Viana
Brucki, Sonia Maria Dozzi
author_facet Sousa, Nariana Mattos Figueiredo
Neri, Ana Cristina da Mata
Brandi, Ivar Viana
Brucki, Sonia Maria Dozzi
author_sort Sousa, Nariana Mattos Figueiredo
collection PubMed
description Pharmacological treatments for mild cognitive impairment (MCI), are lacking, and alternative approaches have been implemented, including cognitive training (CT). OBJECTIVE: To determine the impact of CT on cognitive and quality of life measures in patients with Parkinson’s disease (PD) who were seen a hospital neurorehabilitation program. METHODS: Thirty-nine individuals with MCI-PD, according to the Movement Disorder Society, were randomly distributed into two groups: experimental and control group, matched for demographic and clinical characteristics. Both groups were assessed for cognition and quality of life at the beginning of the study and at the end of the intervention protocol. The following instruments were used to assess cognition and quality of life: Addenbrooke’s Cognitive Examination III, Digit Span, Trail Making Test (TMT, A and B) and Parkinson disease quality of life questionnaire. The experimental group (EG) engaged in CT, whereas the control group (CG) underwent activities of the general rehabilitation program. RESULTS: No baseline evaluation differences were found. Intergroup analysis showed differences in measures, such as total score (1.977, p=0.0480) and visuospatial domain (-2.636, p=0.0084) of the ACE-III, with the EG performing better, in addition to better performance in TMT-B mistakes (-1.928, p=0.0439). Intragroup analysis revealed that the EG showed significant improvement in almost all the cognitive variables, well as in self-reported quality of life (total score and mobility, activities of daily living, body discomfort dimensions). CONCLUSIONS: Engagement in cognitive activities was associated with better cognitive abilities in PD-MCI. Future studies should consider the long-term effect of this type of intervention and impact on functional activities.
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spelling pubmed-80495752021-04-26 Impact of cognitive intervention on cognitive symptoms and quality of life in idiopathic Parkinson’s disease: a randomized and controlled study Sousa, Nariana Mattos Figueiredo Neri, Ana Cristina da Mata Brandi, Ivar Viana Brucki, Sonia Maria Dozzi Dement Neuropsychol Original Article Pharmacological treatments for mild cognitive impairment (MCI), are lacking, and alternative approaches have been implemented, including cognitive training (CT). OBJECTIVE: To determine the impact of CT on cognitive and quality of life measures in patients with Parkinson’s disease (PD) who were seen a hospital neurorehabilitation program. METHODS: Thirty-nine individuals with MCI-PD, according to the Movement Disorder Society, were randomly distributed into two groups: experimental and control group, matched for demographic and clinical characteristics. Both groups were assessed for cognition and quality of life at the beginning of the study and at the end of the intervention protocol. The following instruments were used to assess cognition and quality of life: Addenbrooke’s Cognitive Examination III, Digit Span, Trail Making Test (TMT, A and B) and Parkinson disease quality of life questionnaire. The experimental group (EG) engaged in CT, whereas the control group (CG) underwent activities of the general rehabilitation program. RESULTS: No baseline evaluation differences were found. Intergroup analysis showed differences in measures, such as total score (1.977, p=0.0480) and visuospatial domain (-2.636, p=0.0084) of the ACE-III, with the EG performing better, in addition to better performance in TMT-B mistakes (-1.928, p=0.0439). Intragroup analysis revealed that the EG showed significant improvement in almost all the cognitive variables, well as in self-reported quality of life (total score and mobility, activities of daily living, body discomfort dimensions). CONCLUSIONS: Engagement in cognitive activities was associated with better cognitive abilities in PD-MCI. Future studies should consider the long-term effect of this type of intervention and impact on functional activities. Associação de Neurologia Cognitiva e do Comportamento 2021 /pmc/articles/PMC8049575/ /pubmed/33907597 http://dx.doi.org/10.1590/1980-57642021dn15-010005 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Original Article
Sousa, Nariana Mattos Figueiredo
Neri, Ana Cristina da Mata
Brandi, Ivar Viana
Brucki, Sonia Maria Dozzi
Impact of cognitive intervention on cognitive symptoms and quality of life in idiopathic Parkinson’s disease: a randomized and controlled study
title Impact of cognitive intervention on cognitive symptoms and quality of life in idiopathic Parkinson’s disease: a randomized and controlled study
title_full Impact of cognitive intervention on cognitive symptoms and quality of life in idiopathic Parkinson’s disease: a randomized and controlled study
title_fullStr Impact of cognitive intervention on cognitive symptoms and quality of life in idiopathic Parkinson’s disease: a randomized and controlled study
title_full_unstemmed Impact of cognitive intervention on cognitive symptoms and quality of life in idiopathic Parkinson’s disease: a randomized and controlled study
title_short Impact of cognitive intervention on cognitive symptoms and quality of life in idiopathic Parkinson’s disease: a randomized and controlled study
title_sort impact of cognitive intervention on cognitive symptoms and quality of life in idiopathic parkinson’s disease: a randomized and controlled study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049575/
https://www.ncbi.nlm.nih.gov/pubmed/33907597
http://dx.doi.org/10.1590/1980-57642021dn15-010005
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