Update in the Management of ANCA-Associated Vasculitis: Recent Developments and Future Perspectives

Significant progress has been made in the treatment of ANCA-associated vasculitides (AAV), notably in granulomatosis with polyangiitis and microscopic polyangiitis. Over the past few years, many innovative studies have changed the way we now induce and maintain remission in AAV; achieving remission...

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Detalles Bibliográficos
Autores principales: Samman, Karla N., Ross, Carolyn, Pagnoux, Christian, Makhzoum, Jean-Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049818/
https://www.ncbi.nlm.nih.gov/pubmed/33927768
http://dx.doi.org/10.1155/2021/5534851
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author Samman, Karla N.
Ross, Carolyn
Pagnoux, Christian
Makhzoum, Jean-Paul
author_facet Samman, Karla N.
Ross, Carolyn
Pagnoux, Christian
Makhzoum, Jean-Paul
author_sort Samman, Karla N.
collection PubMed
description Significant progress has been made in the treatment of ANCA-associated vasculitides (AAV), notably in granulomatosis with polyangiitis and microscopic polyangiitis. Over the past few years, many innovative studies have changed the way we now induce and maintain remission in AAV; achieving remission while limiting treatment toxicity is the key. This article provides an in-depth, up-to-date summary of recent trials and suggests treatment algorithms for induction and maintenance of remission based on the latest guidelines. Future possible therapies in AAV will also be discussed.
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spelling pubmed-80498182021-04-28 Update in the Management of ANCA-Associated Vasculitis: Recent Developments and Future Perspectives Samman, Karla N. Ross, Carolyn Pagnoux, Christian Makhzoum, Jean-Paul Int J Rheumatol Review Article Significant progress has been made in the treatment of ANCA-associated vasculitides (AAV), notably in granulomatosis with polyangiitis and microscopic polyangiitis. Over the past few years, many innovative studies have changed the way we now induce and maintain remission in AAV; achieving remission while limiting treatment toxicity is the key. This article provides an in-depth, up-to-date summary of recent trials and suggests treatment algorithms for induction and maintenance of remission based on the latest guidelines. Future possible therapies in AAV will also be discussed. Hindawi 2021-04-08 /pmc/articles/PMC8049818/ /pubmed/33927768 http://dx.doi.org/10.1155/2021/5534851 Text en Copyright © 2021 Karla N. Samman et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Samman, Karla N.
Ross, Carolyn
Pagnoux, Christian
Makhzoum, Jean-Paul
Update in the Management of ANCA-Associated Vasculitis: Recent Developments and Future Perspectives
title Update in the Management of ANCA-Associated Vasculitis: Recent Developments and Future Perspectives
title_full Update in the Management of ANCA-Associated Vasculitis: Recent Developments and Future Perspectives
title_fullStr Update in the Management of ANCA-Associated Vasculitis: Recent Developments and Future Perspectives
title_full_unstemmed Update in the Management of ANCA-Associated Vasculitis: Recent Developments and Future Perspectives
title_short Update in the Management of ANCA-Associated Vasculitis: Recent Developments and Future Perspectives
title_sort update in the management of anca-associated vasculitis: recent developments and future perspectives
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049818/
https://www.ncbi.nlm.nih.gov/pubmed/33927768
http://dx.doi.org/10.1155/2021/5534851
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AT pagnouxchristian updateinthemanagementofancaassociatedvasculitisrecentdevelopmentsandfutureperspectives
AT makhzoumjeanpaul updateinthemanagementofancaassociatedvasculitisrecentdevelopmentsandfutureperspectives

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