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Influence of Electric Current and Magnetic Flow on Firing Patterns of Pre-Bötzinger Complex Model
The dynamics of neuronal firing activity is vital for understanding the pathological respiratory rhythm. Studies on electrophysiology show that the magnetic flow is an essential factor that modulates the firing activities of neurons. By adding the magnetic flow to Butera's neuron model, we inve...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049835/ https://www.ncbi.nlm.nih.gov/pubmed/33927757 http://dx.doi.org/10.1155/2021/6655933 |
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author | Ji, Wenchao Liu, Moutian Duan, Lixia |
author_facet | Ji, Wenchao Liu, Moutian Duan, Lixia |
author_sort | Ji, Wenchao |
collection | PubMed |
description | The dynamics of neuronal firing activity is vital for understanding the pathological respiratory rhythm. Studies on electrophysiology show that the magnetic flow is an essential factor that modulates the firing activities of neurons. By adding the magnetic flow to Butera's neuron model, we investigate how the electric current and magnetic flow influence neuronal activities under certain parametric restrictions. Using fast-slow decomposition and bifurcation analysis, we show that the variation of external electric current and magnetic flow leads to the change of the bistable structure of the system and hence results in the switch of neuronal firing pattern from one type to another. |
format | Online Article Text |
id | pubmed-8049835 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-80498352021-04-28 Influence of Electric Current and Magnetic Flow on Firing Patterns of Pre-Bötzinger Complex Model Ji, Wenchao Liu, Moutian Duan, Lixia Neural Plast Research Article The dynamics of neuronal firing activity is vital for understanding the pathological respiratory rhythm. Studies on electrophysiology show that the magnetic flow is an essential factor that modulates the firing activities of neurons. By adding the magnetic flow to Butera's neuron model, we investigate how the electric current and magnetic flow influence neuronal activities under certain parametric restrictions. Using fast-slow decomposition and bifurcation analysis, we show that the variation of external electric current and magnetic flow leads to the change of the bistable structure of the system and hence results in the switch of neuronal firing pattern from one type to another. Hindawi 2021-04-04 /pmc/articles/PMC8049835/ /pubmed/33927757 http://dx.doi.org/10.1155/2021/6655933 Text en Copyright © 2021 Wenchao Ji et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Ji, Wenchao Liu, Moutian Duan, Lixia Influence of Electric Current and Magnetic Flow on Firing Patterns of Pre-Bötzinger Complex Model |
title | Influence of Electric Current and Magnetic Flow on Firing Patterns of Pre-Bötzinger Complex Model |
title_full | Influence of Electric Current and Magnetic Flow on Firing Patterns of Pre-Bötzinger Complex Model |
title_fullStr | Influence of Electric Current and Magnetic Flow on Firing Patterns of Pre-Bötzinger Complex Model |
title_full_unstemmed | Influence of Electric Current and Magnetic Flow on Firing Patterns of Pre-Bötzinger Complex Model |
title_short | Influence of Electric Current and Magnetic Flow on Firing Patterns of Pre-Bötzinger Complex Model |
title_sort | influence of electric current and magnetic flow on firing patterns of pre-bötzinger complex model |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049835/ https://www.ncbi.nlm.nih.gov/pubmed/33927757 http://dx.doi.org/10.1155/2021/6655933 |
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