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Synthesis of phosphonate derivatives of 2′-deoxy-2′-fluorotetradialdose d-nucleosides and tetradialdose d-nucleosides
Analogs of nucleosides and nucleotides represent a promising pool of potential therapeutics. This work describes a new synthetic route leading to 2′-deoxy-2′-fluorotetradialdose D-nucleoside phosphonates. Moreover, a new universal synthetic route leading to tetradialdose d-nucleosides bearing purine...
Autores principales: | Lášek, Tomáš, Dobiáš, Juraj, Buděšínský, Miloš, Kozák, Jaroslav, Lapuníková, Barbora, Rosenberg, Ivan, Birkuš, Gabriel, Páv, Ondřej |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049856/ https://www.ncbi.nlm.nih.gov/pubmed/33879930 http://dx.doi.org/10.1016/j.tet.2021.132159 |
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