Phosphatidylinositol-3 kinase signaling controls survival and stemness of hematopoietic stem and progenitor cells

Hematopoietic stem and progenitor cells (HSPCs) are multipotent cells giving rise to all blood lineages during life. HSPCs emerge from the ventral wall of the dorsal aorta (VDA) during a specific timespan in embryonic development through endothelial hematopoietic transition (EHT). We investigated th...

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Detalles Bibliográficos
Autores principales: Blokzijl-Franke, Sasja, Ponsioen, Bas, Schulte-Merker, Stefan, Herbomel, Philippe, Kissa, Karima, Choorapoikayil, Suma, den Hertog, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049872/
https://www.ncbi.nlm.nih.gov/pubmed/33714985
http://dx.doi.org/10.1038/s41388-021-01733-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049872/
https://www.ncbi.nlm.nih.gov/pubmed/33714985
http://dx.doi.org/10.1038/s41388-021-01733-5

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