MRP4 over-expression has a role on both reducing nitric oxide-dependent antiplatelet effect and enhancing ADP induced platelet activation

The impact of inhibition of multidrug resistance protein 4 (MRP4) on nitric oxide (NO) resistance and on ADP-induced platelet aggregation is unknown. The aim of this investigation was to verify whether platelet NO resistance correlates with MRP4 expression and evaluate whether this can be reduced by...

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Detalles Bibliográficos
Autores principales: Guarino, Maria Luisa, Massimi, Isabella, Alemanno, Laura, Conti, Laura, Angiolillo, Dominick J., Pulcinelli, Fabio M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049923/
https://www.ncbi.nlm.nih.gov/pubmed/32803738
http://dx.doi.org/10.1007/s11239-020-02214-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049923/
https://www.ncbi.nlm.nih.gov/pubmed/32803738
http://dx.doi.org/10.1007/s11239-020-02214-4

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