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MRP4 over-expression has a role on both reducing nitric oxide-dependent antiplatelet effect and enhancing ADP induced platelet activation
The impact of inhibition of multidrug resistance protein 4 (MRP4) on nitric oxide (NO) resistance and on ADP-induced platelet aggregation is unknown. The aim of this investigation was to verify whether platelet NO resistance correlates with MRP4 expression and evaluate whether this can be reduced by...
Autores principales: | Guarino, Maria Luisa, Massimi, Isabella, Alemanno, Laura, Conti, Laura, Angiolillo, Dominick J., Pulcinelli, Fabio M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049923/ https://www.ncbi.nlm.nih.gov/pubmed/32803738 http://dx.doi.org/10.1007/s11239-020-02214-4 |
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