Sarcoma IL-12 overexpression facilitates NK cell immunomodulation

Interleukin-12 (IL-12) is an inflammatory cytokine that has demonstrated efficacy for cancer immunotherapy, but systemic administration has detrimental toxicities. Lentiviral transduction eliciting IL-12-producing human sarcoma for autologous reintroduction provides localized delivery for both innat...

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Detalles Bibliográficos
Autores principales: Rademacher, Mary Jo, Cruz, Anahi, Faber, Mary, Oldham, Robyn A. A., Wang, Dandan, Medin, Jeffrey A., Schloemer, Nathan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050085/
https://www.ncbi.nlm.nih.gov/pubmed/33859303
http://dx.doi.org/10.1038/s41598-021-87700-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050085/
https://www.ncbi.nlm.nih.gov/pubmed/33859303
http://dx.doi.org/10.1038/s41598-021-87700-2

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