Chemical characterization (LC–MS–ESI), cytotoxic activity and intracellular localization of PAMAM G4 in leukemia cells

Generation 4 of polyamidoamine dendrimer (G4-PAMAM) has several biological effects due to its tridimensional globular structure, repetitive branched amides, tertiary amines, and amino-terminal subunit groups liked to a common core. G4-PAMAM is cytotoxic due to its positive charges. However, its cyto...

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Detalles Bibliográficos
Autores principales: Flores-Mejía, R., Fragoso-Vázquez, M. J., Pérez-Blas, L. G., Parra-Barrera, A., Hernández-Castro, S. S., Estrada-Pérez, A. R., Rodrígues, J., Lara-Padilla, E., Ortiz-Morales, A., Correa-Basurto, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050087/
https://www.ncbi.nlm.nih.gov/pubmed/33859258
http://dx.doi.org/10.1038/s41598-021-87560-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050087/
https://www.ncbi.nlm.nih.gov/pubmed/33859258
http://dx.doi.org/10.1038/s41598-021-87560-w

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