Macrophages with reduced expressions of classical M1 and M2 surface markers in human bronchoalveolar lavage fluid exhibit pro-inflammatory gene signatures

The classical M1/M2 polarity of macrophages may not be applicable to inflammatory lung diseases including chronic obstructive pulmonary disease (COPD) due to the complex microenvironment in lungs and the plasticity of macrophages. We examined macrophage sub-phenotypes in bronchoalveolar lavage (BAL)...

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Detalles Bibliográficos
Autores principales: Takiguchi, Hiroto, Yang, Chen X., Yang, Cheng Wei Tony, Sahin, Basak, Whalen, Beth A., Milne, Stephen, Akata, Kentaro, Yamasaki, Kei, Yang, Julia Shun Wei, Cheung, Chung Yan, Vander Werff, Ryan, McNagny, Kelly M., Leitao Filho, Fernando Sergio, Shaipanich, Tawimas, van Eeden, Stephan F., Obeidat, Ma’en, Leung, Janice M., Sin, Don D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050093/
https://www.ncbi.nlm.nih.gov/pubmed/33859282
http://dx.doi.org/10.1038/s41598-021-87720-y

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