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Interleukin-37 regulates innate immune signaling in human and mouse colonic organoids
Intestinal epithelial cells (IEC) reside in close proximity to the gut microbiota and are hypo-responsive to bacterial products, likely to prevent maladaptive inflammatory responses. This is in part due to their strong expression of Single Ig IL-1 related receptor (SIGIRR), a negative regulator of i...
Autores principales: | Allaire, Joannie M., Poon, Anita, Crowley, Shauna M., Han, Xiao, Sharafian, Zohreh, Moore, Navjit, Stahl, Martin, Bressler, Brian, Lavoie, Pascal M., Jacobson, Kevan, Li, Xiaoxia, Vallance, Bruce A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050237/ https://www.ncbi.nlm.nih.gov/pubmed/33859245 http://dx.doi.org/10.1038/s41598-021-87592-2 |
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