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A rebinding-assay for measuring extreme kinetics using label-free biosensors
In vitro kinetic measurements allow mechanistic characterization of binding interactions and are particularly valuable throughout drug discovery, from confirmation of on-target binding in early discovery to fine-tuning of drug-binding properties in pre-clinical development. Early chemical matter oft...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050309/ https://www.ncbi.nlm.nih.gov/pubmed/33859320 http://dx.doi.org/10.1038/s41598-021-87880-x |