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Tissue plasminogen activator is a ligand of cation-independent mannose 6-phosphate receptor and consists of glycoforms that contain mannose 6-phosphate

Plasmin is the key enzyme in fibrinolysis. Upon interaction with plasminogen activators, the zymogen plasminogen is converted to active plasmin. Some studies indicate plasminogen activation is regulated by cation-independent mannose 6-phosphate receptor (CI-MPR), a protein that facilitates lysosomal...

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Detalles Bibliográficos
Autores principales:	Miller, James J., Bohnsack, Richard N., Olson, Linda J., Ishihara, Mayumi, Aoki, Kazuhiro, Tiemeyer, Michael, Dahms, Nancy M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050316/ https://www.ncbi.nlm.nih.gov/pubmed/33859256 http://dx.doi.org/10.1038/s41598-021-87579-z

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