Cargando…

Evidence for tmTNF reverse signaling in vivo: Implications for an arginase-1-mediated therapeutic effect of TNF inhibitors during inflammation

In order to ascertain the significance of transmembrane tumor necrosis factor (tmTNF) reverse signaling in vivo, we generated a triple transgenic mouse model (3TG, TNFR1−/−, TNFR2−/−, and tmTNFKI/KI) in which all canonical tumor necrosis factor (TNF) signaling was abolished. In bone-marrow-derived m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Diallo, Katy, Simons, Numa, Sayegh, Souraya, Baron, Michel, Degboé, Yannick, Boyer, Jean-Frédéric, Kruglov, Andrey, Nedospasov, Sergei, Novarino, Julien, Aloulou, Meryem, Fazilleau, Nicolas, Constantin, Arnaud, Cantagrel, Alain, Davignon, Jean-Luc, Rauwel, Benjamin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050384/ https://www.ncbi.nlm.nih.gov/pubmed/33889824 http://dx.doi.org/10.1016/j.isci.2021.102331

Ejemplares similares

Rheumatoid Synovial Fluids Regulate the Immunomodulatory Potential of Adipose-Derived Mesenchymal Stem Cells Through a TNF/NF-κB-Dependent Mechanism
por: Sayegh, Souraya, et al.
Publicado: (2019)

Corrigendum: Rheumatoid Synovial Fluids Regulate the Immunomodulatory Potential of Adipose-Derived Mesenchymal Stem Cells Through a TNF/NF-κB-Dependent Mechanism
por: Sayegh, Souraya, et al.
Publicado: (2019)

In vitro response pattern of monocytes after tmTNF reverse signaling predicts response to anti-TNF therapy in rheumatoid arthritis
por: Meusch, Undine, et al.
Publicado: (2015)

Deficient spontaneous in vitro apoptosis and increased tmTNF reverse signaling-induced apoptosis of monocytes predict suboptimal therapeutic response of rheumatoid arthritis to TNF inhibition
por: Meusch, Undine, et al.
Publicado: (2013)

Modulation of T-cell responses by anti-tumor necrosis factor treatments in rheumatoid arthritis: a review
por: Davignon, Jean-Luc, et al.
Publicado: (2018)

Anti-TNF certolizumab pegol induces antioxidant response in human monocytes via reverse signaling
por: Boyer, Jean Frédéric, et al.
Publicado: (2016)

Polarization of Rheumatoid Macrophages by TNF Targeting Through an IL-10/STAT3 Mechanism
por: Degboé, Yannick, et al.
Publicado: (2019)

Contrasting contributions of TNF from distinct cellular sources in arthritis
por: Kruglov, Andrey, et al.
Publicado: (2020)

LTα, TNF, and ILC3 in Peyer’s Patch Organogenesis
por: Gogoleva, Violetta S., et al.
Publicado: (2022)

Several Follicular Regulatory T Cell Subsets With Distinct Phenotype and Function Emerge During Germinal Center Reactions
por: Fazilleau, Nicolas, et al.
Publicado: (2018)

Regulation of B cell responses by distinct populations of CD4 T cells
por: Aloulou, Meryem, et al.
Publicado: (2019)

Current Perspectives on the Role of TNF in Hematopoiesis Using Mice With Humanization of TNF/LT System
por: Gogoleva, Violetta S., et al.
Publicado: (2021)

TNF hampers intestinal tissue repair in colitis by restricting IL-22 bioavailability
por: Ninnemann, Justus, et al.
Publicado: (2022)

Reduced progression of bone erosion in cytomegalovirus seropositive rheumatoid arthritis patients
por: Rauwel, B., et al.
Publicado: (2020)

Interconnected subsets of memory follicular helper T cells have different effector functions
por: Asrir, Assia, et al.
Publicado: (2017)

A Novel Role for Tm7sf2 Gene in Regulating TNFα Expression
por: Bellezza, Ilaria, et al.
Publicado: (2013)

Properties of Fluorescent Far-Red Anti-TNF Nanobodies
por: Gorshkova, Ekaterina N., et al.
Publicado: (2018)

TNFα is responsible for the canonical offspring number-size trade-off
por: Maslennikova, S. O., et al.
Publicado: (2019)

TNF Neutralization Results in the Delay of Transplantable Tumor Growth and Reduced MDSC Accumulation
por: Atretkhany, Kamar-Sulu N., et al.
Publicado: (2016)

TNF and anti-TNF agents in Behçet's disease
por: Calamia, KT
Publicado: (2003)

Dual Role of TNF and LTα in Carcinogenesis as Implicated by Studies in Mice
por: Gubernatorova, Ekaterina O., et al.
Publicado: (2021)

Therapeutic Potential of Combining IL-6 and TNF Blockade in a Mouse Model of Allergic Asthma
por: Namakanova, Olga A., et al.
Publicado: (2022)

Arecoline induces TNF-alpha production and Zonula Occludens-1 redistribution in mouse Sertoli TM4 cells
por: Kuo, Tzer-Min, et al.
Publicado: (2014)

Transmembrane TNF-dependent uptake of anti-TNF antibodies
por: Deora, Arun, et al.
Publicado: (2017)

Autonomous TNF is critical for in vivo monocyte survival in steady state and inflammation
por: Wolf, Yochai, et al.
Publicado: (2017)

Microbiota, Intestinal Immunity, and Mouse Bustle
por: Kruglov, A. A., et al.
Publicado: (2014)

Modulation of pro-inflammatory activation of monocytes and dendritic cells by aza-bis-phosphonate dendrimer as an experimental therapeutic agent
por: Degboé, Yannick, et al.
Publicado: (2014)

New approaches to inhibiting TNF production in rheumatoid arthritis: is pathological TNF regulated in the same way as protective TNF?
por: Feldmann, M, et al.
Publicado: (2001)

Anti-TNF Withdrawal in Inflammatory Bowel Disease
por: Torres, Joana, et al.
Publicado: (2016)

Membrane-Bound TNF Induces Protective Immune Responses to M. bovis BCG Infection: Regulation of memTNF and TNF Receptors Comparing Two memTNF Molecules
por: Olleros, Maria L., et al.
Publicado: (2012)

Anti-TNF drives regulatory T cell expansion by paradoxically promoting membrane TNF–TNF-RII binding in rheumatoid arthritis
por: Nguyen, Dao Xuan, et al.
Publicado: (2016)

Effects of TNFα receptor TNF-Rp55- or TNF-Rp75- deficiency on corneal neovascularization and lymphangiogenesis in the mouse
por: Maier, Anna-Karina B., et al.
Publicado: (2021)

Characterization of In Vitro Engineered Human Adipose Tissues: Relevant Adipokine Secretion and Impact of TNF-α
por: Aubin, Kim, et al.
Publicado: (2015)

The fiendish behavior of TNF can be counteracted by microRNA
por: Cavaillon, Jean-Marc
Publicado: (2015)

Transmembrane TNF-α: structure, function and interaction with anti-TNF agents
por: Horiuchi, Takahiko, et al.
Publicado: (2010)

C-tag TNF: a reporter system to study TNF shedding
por: Pinci, Francesca, et al.
Publicado: (2021)

Comparative Analysis of TNF-alpha, TNF-R1, and TNF-R2 in Patients with Low-impact Fractures Due to Osteoporosis
por: Teixeira, Abel Oliveira Marques, et al.
Publicado: (2023)

Evolution of radiographic joint damage in rituximab-treated versus TNF-treated rheumatoid arthritis cases with inadequate response to TNF antagonists
por: Finckh, Axel, et al.
Publicado: (2012)

Follicular regulatory T cells can be specific for the immunizing antigen and derive from naive T cells
por: Aloulou, Meryem, et al.
Publicado: (2016)

Immunogenicity of TNF-Inhibitors
por: Atiqi, Sadaf, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_n0id3bkntkrk17c5vla85f6ba0