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Kv1.5 channels are regulated by PKC-mediated endocytic degradation

The voltage-gated potassium channel Kv1.5 plays important roles in the repolarization of atrial action potentials and regulation of the vascular tone. While the modulation of Kv1.5 function has been well studied, less is known about how the protein levels of Kv1.5 on the cell membrane are regulated....

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Detalles Bibliográficos
Autores principales: Du, Yuan, Wang, Tingzhong, Guo, Jun, Li, Wentao, Yang, Tonghua, Szendrey, Mark, Zhang, Shetuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050386/
https://www.ncbi.nlm.nih.gov/pubmed/33676894
http://dx.doi.org/10.1016/j.jbc.2021.100514

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