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DNA repair and cholesterol-mediated drug efflux induce dose-dependent chemoresistance in nutrient-deprived neuroblastoma cells

Neuroblastoma is a solid, heterogeneous pediatric tumor. Chemotherapy is widely used to treat neuroblastoma. However, dose-dependent responses and chemoresistance mechanisms of neuroblastoma cells to anticancer drugs remain challenging. Here, we investigated the dose-dependent effects of topotecan o...

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Detalles Bibliográficos
Autores principales:	Chae, Soo Yeon, Nam, Dowoon, Hyeon, Do Young, Hong, Areum, Lee, Timothy Dain, Kim, Sujin, Im, Dongjoon, Hong, Jiwon, Kang, Chaewon, Lee, Ji Won, Hwang, Daehee, Lee, Sang-Won, Kim, Hugh I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050388/ https://www.ncbi.nlm.nih.gov/pubmed/33889821 http://dx.doi.org/10.1016/j.isci.2021.102325

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