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Paeoniflorin ameliorates neuropathic pain-induced depression-like behaviors in mice by inhibiting hippocampal neuroinflammation activated via TLR4/NF-κB pathway

Neuropathic pain (NP) that contributes to the comorbidity between pain and depression is a clinical dilemma. Neuroinflammatory responses are known to have potentially important roles in the initiation of NP and depressive mood. In this study, we aimed to investigate the effects of paeoniflorin (PF)...

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Detalles Bibliográficos
Autores principales: Bai, Hualei, Chen, Shize, Yuan, Tiezheng, Xu, Dongyuan, Cui, Songbiao, Li, Xiangdan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050604/
https://www.ncbi.nlm.nih.gov/pubmed/33859062
http://dx.doi.org/10.4196/kjpp.2021.25.3.217