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Paeoniflorin ameliorates neuropathic pain-induced depression-like behaviors in mice by inhibiting hippocampal neuroinflammation activated via TLR4/NF-κB pathway
Neuropathic pain (NP) that contributes to the comorbidity between pain and depression is a clinical dilemma. Neuroinflammatory responses are known to have potentially important roles in the initiation of NP and depressive mood. In this study, we aimed to investigate the effects of paeoniflorin (PF)...
Autores principales: | Bai, Hualei, Chen, Shize, Yuan, Tiezheng, Xu, Dongyuan, Cui, Songbiao, Li, Xiangdan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Physiological Society and The Korean Society of Pharmacology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050604/ https://www.ncbi.nlm.nih.gov/pubmed/33859062 http://dx.doi.org/10.4196/kjpp.2021.25.3.217 |
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