The hierarchical folding dynamics of topologically associating domains are closely related to transcriptional abnormalities in cancers

Recent studies have shown that the three-dimensional (3D) structure of chromatin is associated with cancer progression. However, the roles of the 3D genome structure and its dynamics in cancer remains largely unknown. In this study, we investigated hierarchical topologically associating domain (TAD)...

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Detalles Bibliográficos
Autores principales: Du, Guifang, Li, Hao, Ding, Yang, Jiang, Shuai, Hong, Hao, Gan, Jingbo, Wang, Longteng, Yang, Yuanping, Li, Yinyin, Huang, Xin, Sun, Yu, Tao, Huan, Li, Yaru, Xu, Xiang, Zheng, Yang, Wang, Junting, Bai, Xuemei, Xu, Kang, Li, Yaoshen, Jiang, Qi, Li, Cheng, Chen, Hebing, Bo, Xiaochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050718/
https://www.ncbi.nlm.nih.gov/pubmed/33897976
http://dx.doi.org/10.1016/j.csbj.2021.03.018

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