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Fascin inhibitor increases intratumoral dendritic cell activation and anti-cancer immunity
Fascin protein is the main actin-bundling protein in filopodia and invadopodia, which are critical for tumor cell migration, invasion, and metastasis. Small-molecule fascin inhibitors block tumor invasion and metastasis and increase the overall survival of tumor-bearing mice. Here, we report a findi...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050791/ https://www.ncbi.nlm.nih.gov/pubmed/33826900 http://dx.doi.org/10.1016/j.celrep.2021.108948 |