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Chromatin accessibility landscapes of immune cells in rheumatoid arthritis nominate monocytes in disease pathogenesis

BACKGROUND: Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease that involves a variety of cell types. However, how the epigenetic dysregulations of peripheral immune cells contribute to the pathogenesis of RA still remains largely unclear. RESULTS: Here, we analysed the genome-wide...

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Detalles Bibliográficos
Autores principales: Zong, Dandan, Huang, Beibei, Li, Young, Lu, Yichen, Xiang, Nan, Guo, Chuang, Liu, Qian, Sha, Qing, Du, Pengcheng, Yu, Qiaoni, Zhang, Wen, Cai, Pengfei, Sun, Yanping, Tao, Jinhui, Li, Xiaomei, Cai, Shanbao, Qu, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050920/
https://www.ncbi.nlm.nih.gov/pubmed/33863328
http://dx.doi.org/10.1186/s12915-021-01011-6

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