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Alkaline phosphatase downregulation promotes lung adenocarcinoma metastasis via the c-Myc/RhoA axis

BACKGROUND: Lung adenocarcinoma (LUAD) metastasis significantly reduces patient survival; hence inhibiting the metastatic ability of lung cancer cells will greatly prolong patient survival. Alkaline phosphatase (ALPL), a homodimeric cell surface phosphohydrolase, is reported to play a controversial...

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Detalles Bibliográficos
Autores principales:	Lou, Zhefeng, Lin, Weiwei, Zhao, Huirong, Jiao, Xueli, Wang, Cong, Zhao, He, Liu, Lu, Liu, Yu, Xie, Qipeng, Huang, Xing, Huang, Haishan, Zhao, Lingling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050923/ https://www.ncbi.nlm.nih.gov/pubmed/33858415 http://dx.doi.org/10.1186/s12935-021-01919-7

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