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Toll-like receptor 2 induced senescence in intervertebral disc cells of patients with back pain can be attenuated by o-vanillin

BACKGROUND: There is an increased level of senescent cells and toll-like teceptor-1, -2, -4, and -6 (TLR) expression in degenerating intervertebral discs (IVDs) from back pain patients. However, it is currently not known if the increase in expression of TLRs is related to the senescent cells or if i...

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Detalles Bibliográficos
Autores principales:	Mannarino, Matthew, Cherif, Hosni, Li, Li, Sheng, Kai, Rabau, Oded, Jarzem, Peter, Weber, Michael H., Ouellet, Jean A., Haglund, Lisbet
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051055/ https://www.ncbi.nlm.nih.gov/pubmed/33863359 http://dx.doi.org/10.1186/s13075-021-02504-z

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