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ChIP-BIT2: a software tool to detect weak binding events using a Bayesian integration approach
BACKGROUND: ChIP-seq combines chromatin immunoprecipitation assays with sequencing and identifies genome-wide binding sites for DNA binding proteins. While many binding sites have strong ChIP-seq ‘peak’ observations and are well captured, there are still regions bound by proteins weakly, with a rela...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051094/ https://www.ncbi.nlm.nih.gov/pubmed/33858322 http://dx.doi.org/10.1186/s12859-021-04108-5 |