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Linaclotide for the treatment of refractory lower bowel manifestations of systemic sclerosis

BACKGROUND: Lower gastrointestinal (GI) tract involvement can affect up to 50% of systemic sclerosis (SSc) patients, and may result in malabsorption, pseudo-obstruction, hospitalization, and death. We report our experience with linaclotide, a selective agonist of guanylate cyclase C (GC-C), for SSc...

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Detalles Bibliográficos
Autores principales:	Dein, Eric J., Wigley, Fredrick M., McMahan, Zsuzsanna H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051106/ https://www.ncbi.nlm.nih.gov/pubmed/33858329 http://dx.doi.org/10.1186/s12876-021-01738-0

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