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RRM2 silencing suppresses malignant phenotype and enhances radiosensitivity via activating cGAS/STING signaling pathway in lung adenocarcinoma

BACKGROUND: As one of the most common malignancy, lung adenocarcinoma (LUAD) is characterized by low 5-year survival rate. This research aimed to investigate the effects of ribonucleotide reductase regulatory subunit M2 (RRM2) on malignant biological behaviors and activation of cGAS/STING pathway. W...

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Detalles Bibliográficos
Autores principales:	Jiang, Xueping, Li, Yangyi, Zhang, Nannan, Gao, Yanping, Han, Linzhi, Li, Shuying, Li, Jiali, Liu, Xingyu, Gong, Yan, Xie, Conghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051110/ https://www.ncbi.nlm.nih.gov/pubmed/33858512 http://dx.doi.org/10.1186/s13578-021-00586-5

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