Oxysterols Modulate the Acute Effects of Ethanol on Hippocampal N-Methyl-d-Aspartate Receptors, Long-Term Potentiation, and Learning

Ethanol is a noncompetitive inhibitor of N-methyl-d-aspartate receptors (NMDARs) and acutely disrupts hippocampal synaptic plasticity and learning. In the present study, we examined the effects of oxysterol positive allosteric modulators (PAMs) of NMDARs on ethanol-mediated inhibition of NMDARs, blo...

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Detalles Bibliográficos
Autores principales: Izumi, Yukitoshi, Mennerick, Steven J., Doherty, James J., Zorumski, Charles F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2021
Materias:
Neuropharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051516/
https://www.ncbi.nlm.nih.gov/pubmed/33441369
http://dx.doi.org/10.1124/jpet.120.000376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051516/
https://www.ncbi.nlm.nih.gov/pubmed/33441369
http://dx.doi.org/10.1124/jpet.120.000376

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