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Spontaneous Renal Artery Dissection in COVID-19 Pneumonia: Potential Danger of Cytokine Storm
The coronavirus disease (COVID-19) pandemic has rapidly spread across the globe since its first detection in March 2020. Its widespread manifestations and vascular complications are increasingly being reported even in young and middle-aged patients. Hyperinflammation is a continuum of host's ex...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051521/ https://www.ncbi.nlm.nih.gov/pubmed/33927903 http://dx.doi.org/10.1155/2021/6696443 |
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author | Parmar, Jitendra Patel, Tapan Shah, Sandip Kothari, Jay Dani, Sameer Vyas, Sagar |
author_facet | Parmar, Jitendra Patel, Tapan Shah, Sandip Kothari, Jay Dani, Sameer Vyas, Sagar |
author_sort | Parmar, Jitendra |
collection | PubMed |
description | The coronavirus disease (COVID-19) pandemic has rapidly spread across the globe since its first detection in March 2020. Its widespread manifestations and vascular complications are increasingly being reported even in young and middle-aged patients. Hyperinflammation is a continuum of host's exaggerated inflammatory response representing cytokine dysregulation/storm which produces coagulopathy and vascular endothelial dysfunction, apart from a prothrombotic state. Cytokine storm or direct viral invasion of the vascular endothelial cells through surface angiotensin-converting enzyme 2 receptors may result in endothelial dysfunction which can potentially result in dissection. Only a few case reports have been published in the literature describing vascular dissection without any inciting factors in COVID-19 patients. Herein, we present the first case report of bilateral renal artery dissection in a 41-year-old male patient who recently recovered from COVID-19 and was managed successfully in stages after many medical hurdles. |
format | Online Article Text |
id | pubmed-8051521 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-80515212021-04-28 Spontaneous Renal Artery Dissection in COVID-19 Pneumonia: Potential Danger of Cytokine Storm Parmar, Jitendra Patel, Tapan Shah, Sandip Kothari, Jay Dani, Sameer Vyas, Sagar Case Rep Crit Care Case Report The coronavirus disease (COVID-19) pandemic has rapidly spread across the globe since its first detection in March 2020. Its widespread manifestations and vascular complications are increasingly being reported even in young and middle-aged patients. Hyperinflammation is a continuum of host's exaggerated inflammatory response representing cytokine dysregulation/storm which produces coagulopathy and vascular endothelial dysfunction, apart from a prothrombotic state. Cytokine storm or direct viral invasion of the vascular endothelial cells through surface angiotensin-converting enzyme 2 receptors may result in endothelial dysfunction which can potentially result in dissection. Only a few case reports have been published in the literature describing vascular dissection without any inciting factors in COVID-19 patients. Herein, we present the first case report of bilateral renal artery dissection in a 41-year-old male patient who recently recovered from COVID-19 and was managed successfully in stages after many medical hurdles. Hindawi 2021-04-10 /pmc/articles/PMC8051521/ /pubmed/33927903 http://dx.doi.org/10.1155/2021/6696443 Text en Copyright © 2021 Jitendra Parmar et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Parmar, Jitendra Patel, Tapan Shah, Sandip Kothari, Jay Dani, Sameer Vyas, Sagar Spontaneous Renal Artery Dissection in COVID-19 Pneumonia: Potential Danger of Cytokine Storm |
title | Spontaneous Renal Artery Dissection in COVID-19 Pneumonia: Potential Danger of Cytokine Storm |
title_full | Spontaneous Renal Artery Dissection in COVID-19 Pneumonia: Potential Danger of Cytokine Storm |
title_fullStr | Spontaneous Renal Artery Dissection in COVID-19 Pneumonia: Potential Danger of Cytokine Storm |
title_full_unstemmed | Spontaneous Renal Artery Dissection in COVID-19 Pneumonia: Potential Danger of Cytokine Storm |
title_short | Spontaneous Renal Artery Dissection in COVID-19 Pneumonia: Potential Danger of Cytokine Storm |
title_sort | spontaneous renal artery dissection in covid-19 pneumonia: potential danger of cytokine storm |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051521/ https://www.ncbi.nlm.nih.gov/pubmed/33927903 http://dx.doi.org/10.1155/2021/6696443 |
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