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Comparative evaluation of crestal bone level in patients having low level of Vitamin D treated with dental implant with or without Vitamin D3 supplements

INTRODUCTION: Vitamin D has been shown to play a vital role in bone mineral homeostasis by stimulating the intestinal absorption of calcium and phosphate. The critical role of Vitamin D in bone metabolism triggered the need to evaluate the effect of Vitamin D deficiency and hence replacement of the...

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Autores principales: Garg, Pooja, Ghalaut, Pankaj, Dahiya, Kiran, Ravi, Reena, Sharma, Anshu, Wakure, Poonam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051646/
https://www.ncbi.nlm.nih.gov/pubmed/33897181
http://dx.doi.org/10.4103/njms.NJMS_49_20
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author Garg, Pooja
Ghalaut, Pankaj
Dahiya, Kiran
Ravi, Reena
Sharma, Anshu
Wakure, Poonam
author_facet Garg, Pooja
Ghalaut, Pankaj
Dahiya, Kiran
Ravi, Reena
Sharma, Anshu
Wakure, Poonam
author_sort Garg, Pooja
collection PubMed
description INTRODUCTION: Vitamin D has been shown to play a vital role in bone mineral homeostasis by stimulating the intestinal absorption of calcium and phosphate. The critical role of Vitamin D in bone metabolism triggered the need to evaluate the effect of Vitamin D deficiency and hence replacement of the same on osseointegration of dental implants. This prospective study evaluated the crestal bone level in patients having low level of Vitamin D treated with dental implant with or without Vitamin D3 supplements. MATERIALS AND METHODS: A prospective clinical study was conducted on 32 patients based on the inclusion and exclusion criteria. Patients were divided into two groups on the basis of Vitamin D level < 30 ng/ml (Group I: patients receiving Vitamin D3 supplements, i.e., cholecalciferol 1 g sachet 60,000 IU/month) or <30 ng/ml (Group II: not receiving Vitamin D3 supplements). The crestal bone level measurements were made with the help of Digimizer Image Analysis, MedCalc software. RESULTS: All implants showed clinically acceptable crestal bone level at interval of 1 week (baseline), 3 months, and 6 months. There was a statistically nonsignificant difference seen for the values between the groups (P > 0.05) for all other values at various time intervals. However, there was a statistically significant/highly significant difference seen for the values between the groups (P < 0.01, 0.05) for 3 months distal with higher values for Group I as compared to Group II. CONCLUSION: From the study, it can be concluded that cholecalciferol has systemic effects on accelerating bone formation around titanium implant.
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spelling pubmed-80516462021-04-23 Comparative evaluation of crestal bone level in patients having low level of Vitamin D treated with dental implant with or without Vitamin D3 supplements Garg, Pooja Ghalaut, Pankaj Dahiya, Kiran Ravi, Reena Sharma, Anshu Wakure, Poonam Natl J Maxillofac Surg Original Article INTRODUCTION: Vitamin D has been shown to play a vital role in bone mineral homeostasis by stimulating the intestinal absorption of calcium and phosphate. The critical role of Vitamin D in bone metabolism triggered the need to evaluate the effect of Vitamin D deficiency and hence replacement of the same on osseointegration of dental implants. This prospective study evaluated the crestal bone level in patients having low level of Vitamin D treated with dental implant with or without Vitamin D3 supplements. MATERIALS AND METHODS: A prospective clinical study was conducted on 32 patients based on the inclusion and exclusion criteria. Patients were divided into two groups on the basis of Vitamin D level < 30 ng/ml (Group I: patients receiving Vitamin D3 supplements, i.e., cholecalciferol 1 g sachet 60,000 IU/month) or <30 ng/ml (Group II: not receiving Vitamin D3 supplements). The crestal bone level measurements were made with the help of Digimizer Image Analysis, MedCalc software. RESULTS: All implants showed clinically acceptable crestal bone level at interval of 1 week (baseline), 3 months, and 6 months. There was a statistically nonsignificant difference seen for the values between the groups (P > 0.05) for all other values at various time intervals. However, there was a statistically significant/highly significant difference seen for the values between the groups (P < 0.01, 0.05) for 3 months distal with higher values for Group I as compared to Group II. CONCLUSION: From the study, it can be concluded that cholecalciferol has systemic effects on accelerating bone formation around titanium implant. Wolters Kluwer - Medknow 2020 2020-12-16 /pmc/articles/PMC8051646/ /pubmed/33897181 http://dx.doi.org/10.4103/njms.NJMS_49_20 Text en Copyright: © 2020 National Journal of Maxillofacial Surgery https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Garg, Pooja
Ghalaut, Pankaj
Dahiya, Kiran
Ravi, Reena
Sharma, Anshu
Wakure, Poonam
Comparative evaluation of crestal bone level in patients having low level of Vitamin D treated with dental implant with or without Vitamin D3 supplements
title Comparative evaluation of crestal bone level in patients having low level of Vitamin D treated with dental implant with or without Vitamin D3 supplements
title_full Comparative evaluation of crestal bone level in patients having low level of Vitamin D treated with dental implant with or without Vitamin D3 supplements
title_fullStr Comparative evaluation of crestal bone level in patients having low level of Vitamin D treated with dental implant with or without Vitamin D3 supplements
title_full_unstemmed Comparative evaluation of crestal bone level in patients having low level of Vitamin D treated with dental implant with or without Vitamin D3 supplements
title_short Comparative evaluation of crestal bone level in patients having low level of Vitamin D treated with dental implant with or without Vitamin D3 supplements
title_sort comparative evaluation of crestal bone level in patients having low level of vitamin d treated with dental implant with or without vitamin d3 supplements
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051646/
https://www.ncbi.nlm.nih.gov/pubmed/33897181
http://dx.doi.org/10.4103/njms.NJMS_49_20
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